Approved For Release 2000/08/09: CIA-RDP96-00792ROO0600170001-3
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                              Science Applications international Corporation
                            An Employee-Owned Company
     January 13, 1992
     Virginia Contracting Activity
     PO. Box 46563
     Washington, D.C 200050-6563
     SG1J Attention:
     Reference: MDA908-91-C-0037
     01-0187-07-0406
     SG1J Dear~
     We are providing you with a written Assurance for the "Protection of Human Subjects," that we are in full
     compliance with all applicable laws, federal regulations and DoD instructions, specifically stated below:
     (1) 45 CFR 46 Health and Human Services (HHS) Regulation, "Protection of Human Subjects";
     (2) 10 U.S. C. Section 980, "Limitations on Use of Humans as Experimental Subjects";
          (3) DoD Directive 3216.2 (January 2, 1983), "Protection of Human. Subjects in DoD-supported Re-
     search";
          (4) Federal Register Part II, (June 18, 1991), "Federal Policy for the Protection of Human Subjects; Notices
     and Rules".
     Our assurance of full compliance consists of the following enclosed documents; 1) SAIC Policy on Research
     Involving Human Subjects, 2) Institutional Review Board Standard Operation Procedures, and 3) Resumes
     of Institutional Review Board Members.
     This package is being sent to you for review and endorsement. After reviewing the enclosed material please
     sign below acknowledging that SAIC is in full compliance. If you have any questions, please do not hesitate
     to contact me at (813) 799-0663. Additional inquiries or comments may be addressed to the IRB Chair-
     man, Dr. Garrison Rapmund, 6 Burning Tree Court, Bethesda, MD 20817, (301) 365-1419.
     Sincerely,
     SCIENCE APPLICATIONS INTERNATIONAL CORPORATIOW
     Betty-Muzioi U
     Senior Contract Representative
     enclosures: written as stated
           Received/Satisfactory 9
     (Signature) (Date)
                   1412 Menlo Park CA 94025 - (415) 325-8292
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     '71(Wota Odando. Palo Alto, Seattle, Tucwn
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