i4
                                                                             ;22            1953
                     Ccatalct-Division
                                                                             I-:!=o Ito -'693
                                                        argic &cid   &i!athya3--ida
             IZD
                                                               Dr.
   'References T                  railtiont
                I-[ r@,.-ptember 1953i C---se
                                                                        ELtion vitb@
                      ion
                                                                        lazese =2u a2re
                                -in        end  -ULielr CCMIDIneEL exl@erience covers tb2
                 -tion lDf-@@--rZOt'Z;Uga tbrou&    :its p-p2lication in the f ield of
           prOdUL
           nedicim.
                 2
                           of tb-- 870ove  m--n   corclucl--   that   lM-e5 is a danz;ercus ne@eri
                                                                     'A"hose aspects are r.=e
           und tbst  itbas & potential as a CW and IRT agent-
           tbjj.,6, tily bali n(4. t,@,ought &b,            Ur interest in tbs su'bjezt               :Nr
                                             ut pric:r to c
              nlrziay.  A-, tbis.,>oint their en'V--.uniam is ru@-l@ hi& ezd they am
           se
                                           the reseamh.to a conclurgion.  Twy prcpose
           ve_  r  interested  ln.l;-ax-graing        d
2           that   -the   foiloving    6dbjecto ob--uld'be       i=vestigrtois
                                               maw
                                          v
                                                                                               i7
         .4
                                                                         4M2@

                                                                              '!,:mo ro.  893
                     'h on Alkaloids  of 7-'rgot'
             (13-:L-yZerrLC,- glnd dietby-'I--ide LSD -25)                    22 C-epte=l@er 1--3
                   IL*  Vrq VMIIL   Buy' C6=try 1,.o_m lnter--ste& in obtai ni n  large
                        quant:il@.:Iailof ergot or Its der:LN-ativest  Oita q7aestion
                        .:La predicated  on the fact that exclusive of ercot deriv-
                        atives used In obs@@etrics,,' dru,-,s c;btaineel by s@-nthesis
                        :in un3.imited quantities proiluce con,@-ro3.led effects %.-hicla
                             bette- than thos' obtained by ergat derivatives. There-
                        are
                        for* if arW counl@ry-or group of countries are ]procuring
                        quantities  of  ergot  a2nd/or  its  derivatives  it  must   be   for
                        uses -yet it-iv-ncrn -uo US L-zwentigations.
                        'I=-2.5 in  a potentiz:L eanti-,anxiCA.-Y  r-@7ent an ind:Lcated   by
                        ---terto conductea. In Rural*   See               rts 3873 and
 2                                -In viev of tbis, viiat vmad be     tb@-- effects  of  zt--Bs
                        -.gLppLicaticm to a populace or troops in tems of el
                                                                                 Ivii defense
                        or offensive actionat  2t vould'be well -to &termina We2cion
                        pryenit Teactiow -:Ln humam  beiyts  and  to.  develop  a  posol-Die
                   -C.  It sbcmlcl'be  definitely aetermiztiff@v@L"at qua--tities  of   ergot
                        deri-mt:L-vas (LSD-2,5) vmld be-ide-eded to 'eff2ectively C=-
                        -La=imeue food and -Ater supplies.
                    6.  've  he'-ve  'been  assured"by  tb@  Mascientiex   that   they   V:Lu
             cooperate fully- in anything -.-@ r-uggest. In  tb@l  a  connection  -we  vou:L&
                            adq@tsrters I wag:                       'be2 ustd  to  steer  the
             a-Wreciate    be                _;estions vhich could
             exp--riments e3.on& lin--s vlost useful to CIA aLnd/or other govery,@- t
                                -in no ir.-. R-late ca3.1 for funds froo CZA as Dr
             ag@--neies.  7asm -                  2                                               C,
             and  rstocialtes@are  Interested  enoug@2  to  mrrceed  on  available   3melical
             schoo3. ftmds.,.-'Y@mda v:LU be neede& later vben bu=L-n subjectx are bired
             (wl. approri=&1.421Y VS$l Per balr) for  eyp--ri=nts.  -The  -f  igu--e  of  Ti4l
                            -jzgested as    r--zez,,  tun&.  Ve4VM'P-pprocip-te YIMW
             tbousand'is    a
             rea:tions and rua.=estions'regarding tbia.proposal.
             004so
    8                                                2  -
                                                                                         TE